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Inhibition of STAT3 signaling and induction of SHP1 mediate antiangiogenic and antitumor activities of ergosterol peroxide in U266 multiple myeloma cells

BACKGROUND: Ergosterol peroxide (EP) derived from edible mushroom has been shown to exert anti-tumor activity in several cancer cells. In the present study, anti-angiogenic activity of EP was investigated with the underlying molecular mechanisms in human multiple myeloma U266 cells. RESULTS: Despite...

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Detalhes bibliográficos
Main Authors: Rhee, Yun-Hee, Jeong, Soo-Jin, Lee, Hyo-Jeong, Lee, Hyo-Jung, Koh, Wonil, Jung, Ji Hoon, Kim, Sun-Hee, Sung-Hoon, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292511/
https://ncbi.nlm.nih.gov/pubmed/22260501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-28
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