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Blockade of Toll-Like Receptor 4 Attenuates Morphine Tolerance and Facilitates the Pain Relieving Properties of Morphine

The ventrolateral periaqueductal gray (vlPAG) is an integral locus for morphine action. Although it is clear that glia contribute to the development of morphine tolerance, to date, the investigation of their role has been limited to spinal and medullary loci. Opioids induce a neuroinflammatory respo...

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Bibliografische gegevens
Hoofdauteurs: Eidson, Lori N., Murphy, Anne Z.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787504/
https://ncbi.nlm.nih.gov/pubmed/24089500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1609-13.2013
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