GARP Is Regulated by miRNAs and Controls Latent TGF-β1 Production by Human Regulatory T Cells

GARP is a transmembrane protein present on stimulated human regulatory T lymphocytes (Tregs), but not on other T lymphocytes (Th cells). It presents the latent form of TGF-β1 on the Treg surface. We report here that GARP favors the cleavage of the pro-TGF-β1 precursor and increases the amount of sec...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Gauthy, Emilie, Cuende, Julia, Stockis, Julie, Huygens, Caroline, Lethé, Bernard, Collet, Jean-François, Bommer, Guido, Coulie, Pierre G., Lucas, Sophie
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787020/
https://ncbi.nlm.nih.gov/pubmed/24098777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076186
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker