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The Rho/Rho-associated protein kinase inhibitor fasudil in the protection of endothelial cells against advanced glycation end products through the nuclear factor κB pathway

Accumulating evidence has demonstrated that the Rho/Rho-associated protein kinase (Rho/ROCK) and nuclear factor κB (NF-κB) signaling pathways are involved in the pathogenesis of diabetic vascular injury. In this study, we investigated the beneficial effects of fasudil, a ROCK inhibitor, on vascular...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LU, YUYAN, LI, HAILING, JIAN, WEIXIA, ZHUANG, JIANHUI, WANG, KE, PENG, WENHUI, XU, YAWEI
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786857/
https://ncbi.nlm.nih.gov/pubmed/24137180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2013.1125
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