ROCK inhibitor fasudil attenuated high glucose-induced MCP-1 and VCAM-1 expression and monocyte-endothelial cell adhesion

BACKGROUND: Previous studies suggested that the RhoA/ROCK pathway may contribute to vascular complications in diabetes. The present study was designed to investigate whether ROCK inhibitor fasudil could prevent high glucose-induced monocyte-endothelial cells adhesion, and whether this was related to...

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Main Authors: Li, Hailing, Peng, Wenhui, Jian, Weixia, Li, Yuanmin, Li, Qi, Li, Weiming, Xu, Yawei
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Original Investigation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461463/
https://ncbi.nlm.nih.gov/pubmed/22694757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-11-65
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