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Fasudil or genetic depletion of ROCK1 or ROCK2 induces anxiety-like behaviors

Twenty-nine protein kinase inhibitors have been used to treat human diseases. Out of these, two are Rho-associated protein kinase (ROCK) 1 and 2 inhibitors. The ROCKs heavily influence neuronal architecture and structural plasticity, and ROCKs are putative drug targets for various brain disorders. W...

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Detalhes bibliográficos
Publicado no:Behav Brain Res
Main Authors: Greathouse, Kelsey M., Henderson, Benjamin W., Gentry, Erik G., Herskowitz, Jeremy H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693674/
https://ncbi.nlm.nih.gov/pubmed/31302146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2019.112083
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