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Inhibitory Effects of Vinpocetine on the Progression of Atherosclerosis Are Mediated by Akt/NF-κB Dependent Mechanisms in apoE(-/-) Mice

BACKGROUND: Recent studies have found additional roles for vinpocetine, a potent phosphodiesterase type I inhibitor, in anti-proliferation and anti-inflammation of vascular smooth muscle cells and cancer cells via different mechanisms. In this study, we attempted to investigate whether vinpocetine p...

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Detalhes bibliográficos
Main Authors: Zhuang, Jianhui, Peng, Wenhui, Li, Hailing, Lu, Yuyan, Wang, Ke, Fan, Fan, Li, Shuang, Xu, Yawei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857260/
https://ncbi.nlm.nih.gov/pubmed/24349299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082509
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