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Critical role of Bcl10 in BAFF-regulated NF-κB activation and survival of anergic B cells
Anergy is a key physiological mechanism for restraining self-reactive B cells. A marked portion of peripheral B cells are anergic B cells that largely depend on B cell-activating factor (BAFF) for survival. BAFF activates the canonical and noncanonical NF-κB pathways, both of which are required for...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3786778/ https://ncbi.nlm.nih.gov/pubmed/23087406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102952 |
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