A critical role of TAK1 in B-cell receptor–mediated nuclear factor κB activation

The kinase TAK1 is essential for T-cell receptor (TCR)–mediated nuclear factor κB (NF-κB) activation and T-cell development. However, the role of TAK1 in B-cell receptor (BCR)–mediated NF-κB activation and B-cell development is not clear. Here we show that B-cell–specific deletion of TAK1 impaired t...

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Detalhes bibliográficos
Main Authors: Schuman, James, Chen, Yuhong, Podd, Andrew, Yu, Mei, Liu, Hong-Hsing, Wen, Renren, Chen, Zhijian J., Wang, Demin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680363/
https://ncbi.nlm.nih.gov/pubmed/19196865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-08-176057
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