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Critical role of Bcl10 in BAFF-regulated NF-κB activation and survival of anergic B cells

Anergy is a key physiological mechanism for restraining self-reactive B cells. A marked portion of peripheral B cells are anergic B cells that largely depend on B cell-activating factor (BAFF) for survival. BAFF activates the canonical and noncanonical NF-κB pathways, both of which are required for...

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Detalhes bibliográficos
Main Authors: Yu, Mei, Chen, Yuhong, He, Yinghong, Podd, Andrew, Fu, Guoping, Wright, Jacqueline A., Kleiman, Eden, Khan, Wasif N., Wen, Renren, Wang, Demin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786778/
https://ncbi.nlm.nih.gov/pubmed/23087406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102952
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