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A critical role of Rap1b in B-cell trafficking and marginal zone B-cell development

B-cell development is orchestrated by complex signaling networks. Rap1 is a member of the Ras superfamily of small GTP-binding proteins and has 2 isoforms, Rap1a and Rap1b. Although Rap1 has been suggested to have an important role in a variety of cellular processes, no direct evidence demonstrates...

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Detalhes bibliográficos
Main Authors: Chen, Yuhong, Yu, Mei, Podd, Andrew, Wen, Renren, Chrzanowska-Wodnicka, Magdalena, White, Gilbert C., Wang, Demin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2343596/
https://ncbi.nlm.nih.gov/pubmed/18319399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-12-128140
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