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Rap1b Regulates B Cell Development, Homing, and T Cell-Dependent Humoral Immunity()

Rap1 is a small GTPase that belongs to Ras superfamily. This ubiquitously expressed GTPase is a key regulator of integrin functions. Rap1 exists in two isoforms: Rap1a and Rap1b. Although Rap1 has been extensively studied, its isoform-specific functions in B cells have not been elucidated. In this s...

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Veröffentlicht in:J Immunol
Hauptverfasser: Chu, Haiyan, Awasthi, Aradhana, White, Gilbert C., Chrzanowska-Wodnicka, Magdalena, Malarkannan, Subramaniam
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571460/
https://ncbi.nlm.nih.gov/pubmed/18714009
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