טוען...
Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes
Rap1 GTPases control immune synapse formation and signaling in lymphocytes. However, the precise molecular mechanism by which Rap1 regulates natural killer (NK) cell activation is not known. Using Rap1a or Rap1b knockout mice, we identify Rap1b as the major isoform in NK cells. Its absence significa...
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| Main Authors: | , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The Rockefeller University Press
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2931159/ https://ncbi.nlm.nih.gov/pubmed/20733035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100040 |
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