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Biodegradable multiblock poly(N-2-hydroxypropyl)methacrylamide gemcitabine and paclitaxel conjugates for ovarian cancer cell combination treatment

The synthesis, characterization, and in vitro evaluation of a combination delivery of multiblock poly(N-2-hydroxypropyl)methacrylamide (HPMA), gemcitabine (GEM) and paclitaxel (PTX) conjugates is described in this study. Multiblock copolymer conjugates of a large molecular weight (M(w) > 200 kDa)...

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Dades bibliogràfiques
Autors principals: Larson, Nate, Yang, Jiyuan, Ray, Abhijit, Cheney, Darwin L., Ghandehari, Hamidreza, Kopeček, Jindřich
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786603/
https://ncbi.nlm.nih.gov/pubmed/23827653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2013.06.046
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