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Bio-inspired synthesis yields a tricyclic indoline that selectively resensitizes methicillin-resistant Staphylococcus aureus (MRSA) to β-lactam antibiotics

The continuous emergence of resistant bacteria has become a major worldwide health threat. The current development of new antibacterials has lagged far behind. To discover reagents to fight against resistant bacteria, we initiated a chemical approach by synthesizing and screening a small molecule li...

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Bibliografiset tiedot
Päätekijät: Podoll, Jessica D., Liu, Yongxiang, Chang, Le, Walls, Shane, Wang, Wei, Wang, Xiang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785754/
https://ncbi.nlm.nih.gov/pubmed/24019472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310459110
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