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Critical Analysis of the Successes and Failures of Homology Models of G-protein coupled receptors: Homology modeling of GPCRs: Success and failures

We present a critical assessment of the performance of our homology model refinement method for G-protein coupled receptors (GPCRs), called LITICon, that led to top ranking structures in a recent structure prediction assessment GPCRDOCK2010. GPCRs form the largest class of drug targets for which onl...

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Autori principali: Bhattacharya, Supriyo, Lam, Alfonso Ramon, Li, Hubert, Balaraman, Gouthaman, Niesen, Michiel Jacobus Maria, Vaidehi, Nagarajan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785289/
https://ncbi.nlm.nih.gov/pubmed/23042299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24195
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