The RIP1-Kinase Inhibitor Necrostatin-1 Prevents Osmotic Nephrosis and Contrast-Induced AKI in Mice

The pathophysiology of contrast-induced AKI (CIAKI) is incompletely understood due to the lack of an appropriate in vivo model that demonstrates reduced kidney function before administration of radiocontrast media (RCM). Here, we examine the effects of CIAKI in vitro and introduce a murine ischemia/...

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Main Authors: Linkermann, Andreas, Heller, Jan-Ole, Prókai, Ágnes, Weinberg, Joel M., De Zen, Federica, Himmerkus, Nina, Szabó, Attila J., Bräsen, Jan H., Kunzendorf, Ulrich, Krautwald, Stefan
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2013
Teme:
Basic Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785275/
https://ncbi.nlm.nih.gov/pubmed/23833261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012121169
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