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Dichotomy between RIP1- and RIP3-Mediated Necroptosis in Tumor Necrosis Factor-α–Induced Shock
Tumor necrosis factor receptor (TNFR) signaling may result in survival, apoptosis or programmed necrosis. The latter is called necroptosis if the receptor-interacting protein 1 (RIP1) inhibitor necrostatin-1 (Nec-1) or genetic knockout of RIP3 prevents it. In the lethal mouse model of TNFα-mediated...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
ScholarOne
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3388137/ https://ncbi.nlm.nih.gov/pubmed/22371307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00423 |
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