Dichotomy between RIP1- and RIP3-Mediated Necroptosis in Tumor Necrosis Factor-α–Induced Shock

Tumor necrosis factor receptor (TNFR) signaling may result in survival, apoptosis or programmed necrosis. The latter is called necroptosis if the receptor-interacting protein 1 (RIP1) inhibitor necrostatin-1 (Nec-1) or genetic knockout of RIP3 prevents it. In the lethal mouse model of TNFα-mediated...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Linkermann, Andreas, Bräsen, Jan H, De Zen, Federica, Weinlich, Ricardo, Schwendener, Reto A, Green, Douglas R, Kunzendorf, Ulrich, Krautwald, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: ScholarOne 2012
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388137/
https://ncbi.nlm.nih.gov/pubmed/22371307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00423
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky