Dichotomy between RIP1- and RIP3-Mediated Necroptosis in Tumor Necrosis Factor-α–Induced Shock

Tumor necrosis factor receptor (TNFR) signaling may result in survival, apoptosis or programmed necrosis. The latter is called necroptosis if the receptor-interacting protein 1 (RIP1) inhibitor necrostatin-1 (Nec-1) or genetic knockout of RIP3 prevents it. In the lethal mouse model of TNFα-mediated...

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Bibliografiska uppgifter
Huvudupphovsmän: Linkermann, Andreas, Bräsen, Jan H, De Zen, Federica, Weinlich, Ricardo, Schwendener, Reto A, Green, Douglas R, Kunzendorf, Ulrich, Krautwald, Stefan
Materialtyp: Artigo
Språk:Inglês
Publicerad: ScholarOne 2012
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388137/
https://ncbi.nlm.nih.gov/pubmed/22371307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00423
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