Identification of RIP1 kinase as a specific cellular target of necrostatins

Necroptosis is a cellular mechanism of necrotic cell death induced by apoptotic stimuli in the form of death domain receptor engagement by their respective ligands under conditions where apoptotic execution is prevented. Although it occurs under regulated conditions, necroptotic cell death is charac...

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Bibliografiset tiedot
Julkaisussa:Nat Chem Biol
Päätekijät: Degterev, Alexei, Hitomi, Junichi, Germscheid, Megan, Ch'en, Irene L, Korkina, Olga, Teng, Xin, Abbott, Derek, Cuny, Gregory D, Yuan, Chengye, Wagner, Gerhard, Hedrick, Stephen M, Gerber, Scott A, Lugovskoy, Alexey, Yuan, Junying
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434866/
https://ncbi.nlm.nih.gov/pubmed/18408713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.83
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