Identification of RIP1 kinase as a specific cellular target of necrostatins

Necroptosis is a cellular mechanism of necrotic cell death induced by apoptotic stimuli in the form of death domain receptor engagement by their respective ligands under conditions where apoptotic execution is prevented. Although it occurs under regulated conditions, necroptotic cell death is charac...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Degterev, Alexei, Hitomi, Junichi, Germscheid, Megan, Ch'en, Irene L, Korkina, Olga, Teng, Xin, Abbott, Derek, Cuny, Gregory D, Yuan, Chengye, Wagner, Gerhard, Hedrick, Stephen M, Gerber, Scott A, Lugovskoy, Alexey, Yuan, Junying
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434866/
https://ncbi.nlm.nih.gov/pubmed/18408713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.83
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