Identification of RIP1 kinase as a specific cellular target of necrostatins

Necroptosis is a cellular mechanism of necrotic cell death induced by apoptotic stimuli in the form of death domain receptor engagement by their respective ligands under conditions where apoptotic execution is prevented. Although it occurs under regulated conditions, necroptotic cell death is charac...

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Détails bibliographiques
Publié dans:Nat Chem Biol
Auteurs principaux: Degterev, Alexei, Hitomi, Junichi, Germscheid, Megan, Ch'en, Irene L, Korkina, Olga, Teng, Xin, Abbott, Derek, Cuny, Gregory D, Yuan, Chengye, Wagner, Gerhard, Hedrick, Stephen M, Gerber, Scott A, Lugovskoy, Alexey, Yuan, Junying
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434866/
https://ncbi.nlm.nih.gov/pubmed/18408713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.83
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