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Necrostatin-1 Reduces Histopathology and Improves Functional Outcome After Controlled Cortical Impact In Mice
Necroptosis is a newly identified type of programmed necrosis initiated by activation of tumor necrosis factor alpha (TNF) and Fas. Necrostatin-1 is a specific inhibitor of necroptosis that reduces ischemic tissue damage in experimental stroke models. We previously reported decreased tissue damage a...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2831087/ https://ncbi.nlm.nih.gov/pubmed/18493258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2008.44 |
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