Necrostatin-1 Reduces Histopathology and Improves Functional Outcome After Controlled Cortical Impact In Mice

Necroptosis is a newly identified type of programmed necrosis initiated by activation of tumor necrosis factor alpha (TNF) and Fas. Necrostatin-1 is a specific inhibitor of necroptosis that reduces ischemic tissue damage in experimental stroke models. We previously reported decreased tissue damage a...

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Bibliografiska uppgifter
Huvudupphovsmän: You, Zerong, Savitz, Sean I., Yang, Jinsheng, Degterev, Alexei, Yuan, Junying, Cuny, Gregory D., Moskowitz, Michael A., Whalen, Michael J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831087/
https://ncbi.nlm.nih.gov/pubmed/18493258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2008.44
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