Akt Regulates TNFα Synthesis Downstream of RIP1 Kinase Activation during Necroptosis

Necroptosis is a regulated form of necrotic cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, we investigated the signaling mechanisms controlled by the necroptosis mediator...

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Detalhes bibliográficos
Main Authors: McNamara, Colleen R., Ahuja, Ruchita, Osafo-Addo, Awo D., Barrows, Douglas, Kettenbach, Arminja, Skidan, Igor, Teng, Xin, Cuny, Gregory D., Gerber, Scott, Degterev, Alexei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585731/
https://ncbi.nlm.nih.gov/pubmed/23469174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056576
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