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Trafficking of the EGFR ligand Spitz regulates its signaling activity in polarized tissues
Epidermal growth factor receptor (EGFR) ligands undergo a complex series of processing events during their maturation to active signaling proteins. Like its mammalian homologs, the predominant Drosophila EGFR ligand Spitz is produced as a transmembrane pro-protein. In the secretory pathway, Spitz is...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Company of Biologists
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3784823/ https://ncbi.nlm.nih.gov/pubmed/23902690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.131169 |
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