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A Screen for X-Linked Mutations Affecting Drosophila Photoreceptor Differentiation Identifies Casein Kinase 1α as an Essential Negative Regulator of Wingless Signaling

The Wnt and Hedgehog signaling pathways are essential for normal development and are misregulated in cancer. The casein kinase family of serine/threonine kinases regulates both pathways at multiple levels. However, it has been difficult to determine whether individual members of this family have dis...

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Bibliografiske detaljer
Main Authors: Legent, Kevin, Steinhauer, Josefa, Richard, Magali, Treisman, Jessica E.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276650/
https://ncbi.nlm.nih.gov/pubmed/22095083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.133827
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