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Protein Kinase A-dependent Phosphorylation of Rap1 Regulates Its Membrane Localization and Cell Migration

The small G protein Rap1 can mediate “inside-out signaling” by recruiting effectors to the plasma membrane that signal to pathways involved in cell adhesion and cell migration. This action relies on the membrane association of Rap1, which is dictated by post-translational prenylation as well as by a...

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Detalhes bibliográficos
Main Authors: Takahashi, Maho, Dillon, Tara J., Liu, Chang, Kariya, Yumi, Wang, Zhiping, Stork, Philip J. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784689/
https://ncbi.nlm.nih.gov/pubmed/23946483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.466904
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