Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury

Ferritin plays a central role in iron metabolism and is made of 24 subunits of 2 types: heavy chain and light chain. The ferritin heavy chain (FtH) has ferroxidase activity that is required for iron incorporation and limiting toxicity. The purpose of this study was to investigate the role of FtH in...

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Main Authors: Zarjou, Abolfazl, Bolisetty, Subhashini, Joseph, Reny, Traylor, Amie, Apostolov, Eugene O., Arosio, Paolo, Balla, Jozsef, Verlander, Jill, Darshan, Deepak, Kuhn, Lukas C., Agarwal, Anupam
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784534/
https://ncbi.nlm.nih.gov/pubmed/24018561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67867
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