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Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury

Ferritin plays a central role in iron metabolism and is made of 24 subunits of 2 types: heavy chain and light chain. The ferritin heavy chain (FtH) has ferroxidase activity that is required for iron incorporation and limiting toxicity. The purpose of this study was to investigate the role of FtH in...

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Autores principales: Zarjou, Abolfazl, Bolisetty, Subhashini, Joseph, Reny, Traylor, Amie, Apostolov, Eugene O., Arosio, Paolo, Balla, Jozsef, Verlander, Jill, Darshan, Deepak, Kuhn, Lukas C., Agarwal, Anupam
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784534/
https://ncbi.nlm.nih.gov/pubmed/24018561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67867
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