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Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury

Ferritin plays a central role in iron metabolism and is made of 24 subunits of 2 types: heavy chain and light chain. The ferritin heavy chain (FtH) has ferroxidase activity that is required for iron incorporation and limiting toxicity. The purpose of this study was to investigate the role of FtH in...

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Detalhes bibliográficos
Main Authors: Zarjou, Abolfazl, Bolisetty, Subhashini, Joseph, Reny, Traylor, Amie, Apostolov, Eugene O., Arosio, Paolo, Balla, Jozsef, Verlander, Jill, Darshan, Deepak, Kuhn, Lukas C., Agarwal, Anupam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784534/
https://ncbi.nlm.nih.gov/pubmed/24018561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67867
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