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Heme oxygenase-1 mitigates ferroptosis in renal proximal tubule cells

Ferroptosis is an iron-dependent form of regulated nonapoptotic cell death, which contributes to damage in models of acute kidney injury (AKI). Heme oxygenase-1 (HO-1) is a cytoprotective enzyme induced in response to cellular stress, and is protective against AKI because of its antiapoptotic and an...

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Pubblicato in:Am J Physiol Renal Physiol
Autori principali: Adedoyin, Oreoluwa, Boddu, Ravindra, Traylor, Amie, Lever, Jeremie M., Bolisetty, Subhashini, George, James F., Agarwal, Anupam
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031916/
https://ncbi.nlm.nih.gov/pubmed/28515173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00044.2017
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