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Role of the PD-1 Pathway in the Immune Response

Understanding immunoregulatory mechanisms is essential for the development of novel interventions to improve long-term allograft survival. Programmed death 1 (PD-1) and its ligands, PD-L1 and PD-L2, have emerged as critical inhibitory signaling pathways that regulate T cell response and maintain per...

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Autors principals: Riella, Leonardo V., Paterson, Alison M., Sharpe, Arlene H., Chandraker, Anil
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784243/
https://ncbi.nlm.nih.gov/pubmed/22900886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2012.04224.x
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