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Inhibitors of Difficult Protein-Protein Interactions Identified by High Throughput Screening of Multi-Protein Complexes
Protein-protein interactions (PPIs) are important in all aspects of cellular function and there is interest in finding inhibitors of these contacts. However, PPIs with weak affinities and/or large interfaces have traditionally been more resistant to the discovery of inhibitors, partly because it is...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3783524/ https://ncbi.nlm.nih.gov/pubmed/23819499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400356m |
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