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Enzymatic Synthesis of RNAs Capped with Nucleotide Analogues Reveals the Molecular Basis for Substrate Selectivity of RNA Capping Enzyme: Impacts on RNA Metabolism

RNA cap binding proteins have evolved to specifically bind to the N7-methyl guanosine cap structure found at the 5’ ends of eukaryotic mRNAs. The specificity of RNA capping enzymes towards GTP for the synthesis of this structure is therefore crucial for mRNA metabolism. The fact that ribavirin triph...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Issur, Moheshwarnath, Bougie, Isabelle, Despins, Simon, Bisaillon, Martin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783409/
https://ncbi.nlm.nih.gov/pubmed/24086504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075310
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