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The flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structure
The 5′-end of the flavivirus genome harbors a methylated (m7)GpppA(2′OMe) cap structure, which is generated by the virus-encoded RNA triphosphatase, RNA (guanine-N7) methyltransferase, nucleoside 2′-O-methyltransferase, and RNA guanylyltransferase. The presence of the flavivirus guanylyltransferase...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779676/ https://ncbi.nlm.nih.gov/pubmed/19850911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1609709 |
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