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Deciphering the molecular basis for nucleotide selection by the West Nile virus RNA helicase

The West Nile virus RNA helicase uses the energy derived from the hydrolysis of nucleotides to separate complementary strands of RNA. Although this enzyme has a preference for ATP, the bias towards this purine nucleotide cannot be explained on the basis of specific protein–ATP interactions. Moreover...

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Bibliographic Details
Main Authors: Despins, Simon, Issur, Moheshwarnath, Bougie, Isabelle, Bisaillon, Martin
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938200/
https://ncbi.nlm.nih.gov/pubmed/20421212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq276
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