Nucleotide analogs and molecular modeling studies reveal key interactions involved in substrate recognition by the yeast RNA triphosphatase

RNA triphosphatases (RTPases) are involved in the addition of the distinctive cap structure found at the 5′ ends of eukaryotic mRNAs. Fungi, protozoa and some DNA viruses possess an RTPase that belongs to the triphosphate tunnel metalloenzyme family of enzymes that can also hydrolyze nucleoside trip...

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Bibliografiska uppgifter
Huvudupphovsmän: Issur, Moheshwarnath, Despins, Simon, Bougie, Isabelle, Bisaillon, Martin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2009
Ämnen:
Nucleic Acids Enzymes
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699512/
https://ncbi.nlm.nih.gov/pubmed/19372271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp227
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