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Generation and immunosuppressive functions of p53-induced human adaptive regulatory T cells
Inducible regulatory T cells (iTregs, also called Tr1 cells) are generated in the periphery (circulation or tissue) of cancer patients upon the encounter of naïve CD4(+) T cells with tumor-associated antigens. As p53 is often inactivated by genetic or epigenetic events during oncogenesis, p53-induce...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3782015/ https://ncbi.nlm.nih.gov/pubmed/24073385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.25514 |
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