Blunted Refeeding Response and Increased Locomotor Activity in Mice Lacking FoxO1 in Synapsin-Cre–Expressing Neurons

Successful development of antiobesity agents requires detailed knowledge of neural pathways controlling body weight, eating behavior, and peripheral metabolism. Genetic ablation of FoxO1 in selected hypothalamic neurons decreases food intake, increases energy expenditure, and improves glucose homeos...

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Hlavní autoři: Ren, Hongxia, Plum-Morschel, Leona, Gutierrez-Juarez, Roger, Lu, Taylor Y., Kim-Muller, Ja Young, Heinrich, Garrett, Wardlaw, Sharon L., Silver, Rae, Accili, Domenico
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2013
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781468/
https://ncbi.nlm.nih.gov/pubmed/23835335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0597
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