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SB-205384 Is a Positive Allosteric Modulator of Recombinant GABA(A) Receptors Containing Rat α3, α5, or α6 Subunit Subtypes Coexpressed with β3 and γ2 Subunits
Many drugs used to treat anxiety are positive modulators of GABA(A) receptors, which mediate fast inhibitory neurotransmission. The GABA(A) receptors can be assembled from a combination of at least 16 different subunits. The receptor’s subunit composition determines its pharmacologic and functional...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3781410/ https://ncbi.nlm.nih.gov/pubmed/23902941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.207324 |
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