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RNA editing of the GABA(A) receptor α3 subunit alters the functional properties of recombinant receptors

RNA editing provides a post-transcriptional mechanism to increase structural heterogeneity of gene products. Recently, the α3 subunit of the GABA(A) receptors has been shown to undergo RNA editing. As a result, a highly conserved isoleucine residue in the third transmembrane domain is replaced with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nimmich, Mitchell L., Heidelberg, Laura S., Fisher, Janet L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775542/
https://ncbi.nlm.nih.gov/pubmed/19367790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neures.2009.01.003
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