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SB-205384 Is a Positive Allosteric Modulator of Recombinant GABA(A) Receptors Containing Rat α3, α5, or α6 Subunit Subtypes Coexpressed with β3 and γ2 Subunits

Many drugs used to treat anxiety are positive modulators of GABA(A) receptors, which mediate fast inhibitory neurotransmission. The GABA(A) receptors can be assembled from a combination of at least 16 different subunits. The receptor’s subunit composition determines its pharmacologic and functional...

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書目詳細資料
Main Authors: Heidelberg, Laura S., Warren, James W., Fisher, Janet L.
格式: Artigo
語言:Inglês
出版: The American Society for Pharmacology and Experimental Therapeutics 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781410/
https://ncbi.nlm.nih.gov/pubmed/23902941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.207324
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