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Serum-Free Medium and Mesenchymal Stromal Cells Enhance Functionality and Stabilize Integrity of Rat Hepatocyte Spheroids

Long-term culture of hepatocyte spheroids with high ammonia clearance is valuable for therapeutic applications, especially the bioartificial liver. However, the optimal conditions are not well studied. We hypothesized that liver urea cycle enzymes can be induced by high protein diet and maintain on...

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Huvudupphovsmän: Bao, Ji, Fisher, James E., Lillegard, Joseph B., Wang, William, Amiot, Bruce, Yu, Yue, Dietz, Allan B., Nahmias, Yaakov, Nyberg, Scott L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781336/
https://ncbi.nlm.nih.gov/pubmed/23006214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096368912X656054
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