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Serum-Free Medium and Mesenchymal Stromal Cells Enhance Functionality and Stabilize Integrity of Rat Hepatocyte Spheroids

Long-term culture of hepatocyte spheroids with high ammonia clearance is valuable for therapeutic applications, especially the bioartificial liver. However, the optimal conditions are not well studied. We hypothesized that liver urea cycle enzymes can be induced by high protein diet and maintain on...

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Detalhes bibliográficos
Main Authors: Bao, Ji, Fisher, James E., Lillegard, Joseph B., Wang, William, Amiot, Bruce, Yu, Yue, Dietz, Allan B., Nahmias, Yaakov, Nyberg, Scott L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781336/
https://ncbi.nlm.nih.gov/pubmed/23006214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096368912X656054
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