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Serum-Free Medium and Mesenchymal Stromal Cells Enhance Functionality and Stabilize Integrity of Rat Hepatocyte Spheroids

Long-term culture of hepatocyte spheroids with high ammonia clearance is valuable for therapeutic applications, especially the bioartificial liver. However, the optimal conditions are not well studied. We hypothesized that liver urea cycle enzymes can be induced by high protein diet and maintain on...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bao, Ji, Fisher, James E., Lillegard, Joseph B., Wang, William, Amiot, Bruce, Yu, Yue, Dietz, Allan B., Nahmias, Yaakov, Nyberg, Scott L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781336/
https://ncbi.nlm.nih.gov/pubmed/23006214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096368912X656054
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