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Rat hepatocyte spheroids formed by rocked technique maintain differentiated hepatocyte gene expression and function
The culture of primary hepatocytes as spheroids creates an efficient 3-dimensional tissue construct for hepatic studies in vitro. Spheroids possess structural polarity and functional bile canaliculi with normal differentiated function. Thus, hepatocyte spheroids have been proposed as the cell source...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680349/ https://ncbi.nlm.nih.gov/pubmed/19085959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22674 |
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