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Rat hepatocyte spheroids formed by rocked technique maintain differentiated hepatocyte gene expression and function

The culture of primary hepatocytes as spheroids creates an efficient 3-dimensional tissue construct for hepatic studies in vitro. Spheroids possess structural polarity and functional bile canaliculi with normal differentiated function. Thus, hepatocyte spheroids have been proposed as the cell source...

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Detalhes bibliográficos
Main Authors: Brophy, Colleen M., Luebke-Wheeler, Jennifer L., Amiot, Bruce P., Remmel, Rory P., Rinaldo, Piero, Nyberg, Scott L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680349/
https://ncbi.nlm.nih.gov/pubmed/19085959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22674
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