Temporal clustering of gene expression links the metabolic transcription factor HNF4α to the ER stress-dependent gene regulatory network

The unfolded protein response (UPR) responds to disruption of endoplasmic reticulum (ER) function by initiating signaling cascades that ultimately culminate in extensive transcriptional regulation. Classically, this regulation includes genes encoding ER chaperones, ER-associated degradation factors,...

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Detalhes bibliográficos
Main Authors: Arensdorf, Angela M., DeZwaan McCabe, Diane, Kaufman, Randal J., Rutkowski, D. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781334/
https://ncbi.nlm.nih.gov/pubmed/24069029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00188
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