ER stress inhibits liver fatty acid oxidation while unmitigated stress leads to anorexia-induced lipolysis and both liver and kidney steatosis

The unfolded protein response (UPR), induced by endoplasmic reticulum (ER) stress, regulates the expression of factors that restore protein folding homeostasis. However, in the liver and kidney, ER stress also leads to lipid accumulation, accompanied at least in the liver by transcriptional suppress...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Rep
Päätekijät: DeZwaan-McCabe, Diane, Sheldon, Ryan D., Gorecki, Michelle C., Guo, Deng-Fu, Gansemer, Erica R., Kaufman, Randal J., Rahmouni, Kamal, Gillum, Matthew P., Taylor, Eric B., Teesch, Lynn M., Rutkowski, D. Thomas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520660/
https://ncbi.nlm.nih.gov/pubmed/28564599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.05.020
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