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Dipeptides promote folding and peptide binding of MHC class I molecules

MHC class I molecules bind only those peptides with high affinity that conform to stringent length and sequence requirements. We have now investigated which peptides can aid the in vitro folding of class I molecules, and we find that the dipeptide glycyl-leucine efficiently supports the folding of H...

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Autors principals: Saini, Sunil Kumar, Ostermeir, Katja, Ramnarayan, Venkat Raman, Schuster, Heiko, Zacharias, Martin, Springer, Sebastian
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780906/
https://ncbi.nlm.nih.gov/pubmed/24003162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308672110
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