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Dipeptides catalyze rapid peptide exchange on MHC class I molecules

Peptide ligand selection by MHC class I molecules, which occurs by iterative optimization, is the centerpiece of immunodominance in antiviral and antitumor immune responses. For its understanding, the molecular mechanisms of peptide binding and dissociation by class I molecules must be elucidated. T...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Saini, Sunil Kumar, Schuster, Heiko, Ramnarayan, Venkat Raman, Rammensee, Hans-Georg, Stevanović, Stefan, Springer, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291614/
https://ncbi.nlm.nih.gov/pubmed/25535340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1418690112
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