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Bidirectional binding of invariant chain peptides to an MHC class II molecule
T-cell recognition of peptides bound to MHC class II (MHCII) molecules is a central event in cell-mediated adaptive immunity. The current paradigm holds that prebound class II-associated invariant chain peptides (CLIP) and all subsequent antigens maintain a canonical orientation in the MHCII binding...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3009805/ https://ncbi.nlm.nih.gov/pubmed/21115828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014708107 |
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