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Conformational Flexibility of the MHC Class I α(1)-α(2) Domain in Peptide Bound and Free States: A Molecular Dynamics Simulation Study

Major histocompatibility complex class I proteins play a key role in the recognition and presentation of peptide antigens to the host immune system. The structure of various major histocompatibility complex class I proteins has been determined experimentally in complex with several antigenic peptide...

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Detalhes bibliográficos
Main Authors: Zacharias, Martin, Springer, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304646/
https://ncbi.nlm.nih.gov/pubmed/15454423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.044743
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