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Model for the Peptide-Free Conformation of Class II MHC Proteins

BACKGROUND: Major histocompatibility complex proteins are believed to undergo significant conformational changes concomitant with peptide binding, but structural characterization of these changes has remained elusive. METHODOLOGY/PRINCIPAL FINDINGS: Here we use molecular dynamics simulations and exp...

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Detalhes bibliográficos
Main Authors: Painter, Corrie A., Cruz, Anthony, López, Gustavo E., Stern, Lawrence J., Zavala-Ruiz, Zarixia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408972/
https://ncbi.nlm.nih.gov/pubmed/18545669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002403
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