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Model for the Peptide-Free Conformation of Class II MHC Proteins
BACKGROUND: Major histocompatibility complex proteins are believed to undergo significant conformational changes concomitant with peptide binding, but structural characterization of these changes has remained elusive. METHODOLOGY/PRINCIPAL FINDINGS: Here we use molecular dynamics simulations and exp...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2408972/ https://ncbi.nlm.nih.gov/pubmed/18545669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002403 |
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